Clinical Trials

Johns Hopkins AI Collab to Boost Patient Enrollment in Brain Injury Trial

February 15, 2023 - The BIOS Clinical Trials Coordinating Center (BIOS CTTC) at Johns Hopkins University is partnering with intelligent care coordination software company Viz.ai to boost patient enrollment for the National Institutes of Health (NIH) Biomarker and Edema Attenuation in IntraCerebral Hemorrhage (BEACH) study. According to the press release, the BEACH...

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Machine-Learning Intervention Leads to Safer Cardiac Catheterization

by Mark Melchionna

As reported in the Clinical Journal of the American Society of Nephrology, a randomized trial conducted by Vanderbilt University Medical Center (VUMC), the Dartmouth Geisel School of Medicine, and the...

MN Health System Joins Research Network to Advance Precision Medicine

by Shania Kennedy

Allina Health, a Minnesota-based health system with 12 hospital campuses and over 90 clinics throughout Minnesota and western Wisconsin, has joined the Guardian Research Network (GRN) to expand its...

OR Health System to Test AI App That Tracks Blood Sugar Levels

by Mark Melchionna

After receiving a grant from the Leona M. and Harry B. Helmsley Charitable Trust, Oregon Health and Science University (OHSU) researchers developed an artificial intelligence (AI)-based app to evaluate...

AI May Improve Patient Experience in Decentralized Clinical Trials

by Shania Kennedy

In an article published last month in Nature Medicine, researchers argued that artificial intelligence could improve patient experience in decentralized clinical trials through the use of reinforcement...

AI Supports Clinical Trial for Rare Genetic Disease Treatment

by Mark Melchionna

Artificial intelligence (AI) supported a clinical trial focused on assessing treatment methods for a rare genetic disease known as activity-dependent neuroprotective protein (ADNP) syndrome. ADNP...

Clinical Trials Assessing ML Methods Lack Transparent Reporting, Inclusivity

by Mark Melchionna

A study published in JAMA Network Open found that researchers must improve the randomized clinical trials (RCTs) to test machine-learning (ML) algorithms by making the trials more inclusive and...

Real-World Data Collab Aims to Improve Diversity in Cancer Clinical Trials

by Shania Kennedy

The National Cancer Institute Community Oncology Research Program (NCI NCORP)-designated Louisiana State University (LSU) Health New Orleans is collaborating with artificial intelligence (AI) and...

MA Researchers Create AI Algorithm to Enhance Lung Cancer Radiation Therapy

by Mark Melchionna

Researchers from the Artificial Intelligence (AI) in Medicine Program of Brigham and Women’s Hospital created a deep-learning algorithm to improve lung cancer radiation therapy treatment and...

NY Health Consortium Receives $8M to Expand Patient Data Network

by Shania Kennedy

The Patient-Centered Outcomes Research Institute (PCORI) has awarded nearly $8 million to expand the INSIGHT Clinical Research Network, a Weill Cornell-led database containing EHR and clinical trial...

Voice Biomarker Can Predict Coronary Artery Disease Events

by Mark Melchionna

A research team led by Mayo Clinic created an artificial intelligence (AI) computer-based algorithm that can use voice biomarkers to locate clogged arteries, helping clinicians detect heart...

Data Analytics Highlights Health Disparities In Cancer Clinical Trials

by Erin McNemar, MPA

According to a data analytics study examining health disparities in cancer clinical trials, certain populations remain underrepresented despite attempts to increase participation. By including...

Health Disparities Emerge Around Cancer Screening Eligibility

by Erin McNemar, MPA

According to the results of a simulated pancreatic cancer clinical trial screening, Black patients were significantly more likely than White patients to be excluded from clinical trials due to a wide...

Predictive, Data Analytics Used in Genomic Tests for Prostate Cancer

by Erin McNemar, MPA

Using predictive and data analytics, University of Michigan researchers conducted a study that discovered a commercially available genomic test, Decipher Biopsy, could assist in identifying prostate...

CRISPR Shows Promise in Gene-Editing Therapy During Clinical Trial

by Erin McNemar, MPA

Scientists at UCL National Amyloidosis Centre at the Royal Free Hospital, London are hoping their gene editing therapy using CRISPR will be a breakthrough for patients suffering from hereditary...

Predictive Analytics Model Anticipates Pediatric Blood Clots

by Jessica Kent

Using a predictive analytics model, providers could proactively identify pediatric patients at risk of developing blood clots or venous thromboembolisms (VTEs), according to a study published in...

Gene Therapy Preserves Memory in Alzheimer’s Mouse Model

by Jessica Kent

A team from University of California San Diego School of Medicine has leveraged gene therapy to preserve learning and memory in a mouse model of Alzheimer’s, indicating that the approach could...

Precision Medicine Therapy Improves Congenital Blindness

by Jessica Kent

In an initial clinical trial, researchers found that a new precision medicine therapy for a common form of congenital blindness was safe and improved patients’ vision, according to a study...

Clinical Trial Uses Precision Medicine for Pancreatic Cancer Drugs

by Jessica Kent

The Pancreatic Cancer Action Network (PanCAN) has launched Precision Promise, a precision medicine clinical trial that will aim to improve pancreatic cancer drugs. Moores Cancer Center at UC San Diego...

Genetic Data Identifies Drug Targets to Treat Early COVID-19

by Jessica Kent

An analysis of genetic data indicates that leaders should prioritize clinical trials of two proteins – IFNAR2 and ACE2 – to better treat COVID-19 in its early stages. In a study published...

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